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DeCS
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Descriptor English:
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Fibroblast Growth Factor 2
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Descriptor Spanish:
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Factor 2 de Crecimiento de Fibroblastos
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Descriptor Portuguese:
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Fator 2 de Crescimento de Fibroblastos
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Synonyms English:
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Cartilage-Derived Growth Factor
Class II Heparin-Binding Growth Factor
FGF-2
FGF2
Fibroblast Growth Factor-2
Heparin-Binding Growth Factor Class II
Prostate Epithelial Cell Growth Factor
Prostatropin
Cartilage Derived Growth Factor
FGF 2
Basic Fibroblast Growth Factor
Fibroblast Growth Factor, Basic
HBGF-2
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Tree Number:
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D12.644.276.624.120
D12.776.467.624.120
D23.529.624.120
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Definition English:
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A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1). |
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History Note English:
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2001(1991); for FIBROBLAST GROWTH FACTOR-2 use FIBROBLAST GROWTH FACTOR 2 (NM) 1995; for PROSTATROPIN use FIBROBLAST GROWTH FACTOR 2 (NM) 1986-2001
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Allowable Qualifiers English:
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Record Number:
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28936
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Unique Identifier:
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D016222
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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